單核上皮性腸道T細胞淋巴瘤併長期腹瀉和腸穿孔－－病例報告

Mononorphic Epitheliotropic Intestinal T-cell Lymphoma in the Jejunum of An 80-Year-Old Patient with Long-term Diarrhea and Bowel Perforation

單形上皮性腸T細胞淋巴瘤(MEITL)是一種罕見的侵襲性周邊T細胞淋巴瘤(PTCL)，其起源於腸上皮內T淋巴細胞。我們報告一空腸MEITL患者的病例。該名女性病患出現1個月的水樣腹瀉病史。她因懷疑腸穿孔而接受手術治療，不幸在手術後10天死亡。我們建議對於出現腹痛、長時間腹瀉、體重減輕和吸收不良的患者，應將MEITL視為鑑別診斷的一部分，因為延遲治療可能會導致急性腹部急症及不良後果。

Monomorphic epitheliotropic intestinal T cell lymphoma (MEITL) is a rare and aggressive peripheral T-cell lymphoma (PTCL) that arises from intestinal intraepithelial T lymphocytes. Herein, we report the case of a patient with MEITL in the jejunum. The patient had complained of watery diarrhea that had lasted for one month and was being treated by another clinic. She came to our hospital presenting with severe vomiting and marked weakness. CT showed possible malignancy but further invasive examinations could not be performed due to her poor condition. She was surgically treated for suspected bowel perforation due to sudden worsening of her symptoms. Pathology later revealed MEITL. The patient died ten days after surgery. MEITL should be regarded as part of differential diagnosis in any patient presenting with abdominal pain, prolonged diarrhea, weight loss, and malabsorption. Delay in treatment may cause acute abdominal emergency resulting in a poor outcome.