Acute Psychosis as the Predominant Manifestation in a Patient with Systemic Lupus Erythematosus

Acute Psychosis as the Predominant Manifestation in a Patient with Systemic Lupus Erythematosus

Neuropsychiatric systemic lupus erythematosus (NPSLE) can occur at any time during the course of SLE, even during the remission phase of SLE [1]. A recent meta-analysis showed the prevalence of psychosis is 6.5% among patients with NPSLE [2]. Lupus psychosis is an infrequent symptom of NPSLE and has negative impacts on quality of life and health status. Psychosis as the only manifestation of NPSLE, independent of active SLE, is rare and causes a diagnostic and therapeutic dilemma.