癲癇患者使用改良式阿金氏飲食是否能降低癲癇發作頻率？

The Affect of Modified Atkin’s Diet on Reduction of Seizure Frequency in Patient with Epileptic Disorder

癲癇（Epilepsy）是因腦部細胞陣發性不定期放電造成身體異常活動的慢性腦病變，發作形式依放電部位及頻率而有所不同，因意識喪失及肌肉持續性抽搐而長時間的癲癇發作或反覆發作可能導致持續性癲癇發作狀態（status epilepticus），可能造成約11-16%的患者產生永久性神經傷害或認知功能障礙甚至死亡。
經由實證相關研究發現改良阿特金斯飲食對於改善癲癇發作頻率為有影響，另針對難治性癲癇患者加入MAD作為輔助療法對於降低癲癇發作頻率>50%，以及針對耐藥性癲癇患者接受12週MAD飲食治療對於癲癇發作頻率減少>25%，其研究結果皆具有顯著差異，因此臨床上除藥物治療外可藉由醫師、營養師、護理師等跨領域團隊，推廣改良阿特金斯飲食輔助治療，以達到減少癲癇發生率進而改善病人生活品質。

Epilepsy is a chronic brain disease caused by abnormal physical activity caused by intermittent and irregular discharge of brain cells. The form of seizures varies according to the location and frequency of discharge. Uninterrupted seizure may lead to status epilepticus, which has a high mortality rate and cause permanent brain injury.
Multiple studies have found that the modified Atkins diet (MAD) improves seizure frequency. By adding MAD as adjuvant therapy for patients with refractory epilepsy can reduce seizure frequency by >50%, and for patients with drug-resistant epilepsy for 12 weeks MAD diet therapy can reduce the frequency of epileptic seizures by >25%. Therefore, in addition to drug treatment, in clinical practice, doctors, nutritionists, nurses and other crossdisciplinary teams can promote the modified Atkins diet to reduce the incidence of epilepsy and improve the quality of life of patients.