懷孕中卵巢癌的治療檢視

Ovarian cancer complicated pregnancy

卵巢癌乃孕婦第二常見的婦癌，處理上較複雜，因靠近子宮及其發展中胎兒的附屬器內，放射及化學治療對胎兒皆具不良的影響。腫瘤指數和影像學檢查是對卵巢癌診斷的重要方法，但由於懷孕使很多腫瘤指數會改變，降低診斷的準確性，唯人類副睪蛋白（HE4）在懷孕中較不受影響，確有助益於卵巢癌的診斷和治療。對懷孕中卵巢癌仍建議採手術治療，胎兒盡量保留，其它治療原則大致與非懷孕時相近。

Ovarian cancer is the second most common gynecological cancers diagnosed in pregnancy. Its management is often very problematic due to proximity of the adnexa to the developing fetus and chemotherapy related toxicity risk. Tumor mrakers and imagining studies play important in diagnosis, help differentiate benign masses from malignancy and allow to plan the treatment. Due to the physiological changes that occur in pregnancy, levels of tumor markers can be altered and reduce their diagnostic value. However, human epididymis protein 4 (HE4) are not elevated in normal pregnancy and can be used in both diagnosis and therapy evaluation. There are no guidelines for patients management. Pregnancy should be preserved and continued whenever possible. Cancer treatment during pregnancy, both surgical and systematic is possible, and should adhere as much as possible to the standard protocol of care offered to non-pregnant patients.