男性不孕症方藥規律之研究──以傅青主男科為例

Study of Frequency of Chinese Medicine Prescription for Male Infertility-Mainly by Fu Qingzhu's Medical Department for Men

目的：本研究通過整理、分析傅青主男科治療男性不孕症所用的方藥，以闡明傅青主治療男性不孕症的用藥特點和配伍規律，並和現代中醫治療不孕症觀點結合。材料：本研究以《傅青主男科‧卷上》和《傅青主男科‧卷下》為主探討其對於男性不孕症的用藥規律及用藥頻率。方法：本文收集《傅青主男科‧卷上》和《傅青主男科‧卷下》中所有內服方藥，將所用中藥輸入Excel表格，進行頻數頻率統計，針對藥物功效、歸經的分布進行統計分析。結果：共81味中藥，總頻數為450次；男性不孕症主要病機為腎虛、肝鬱、血虛、血瘀、痰濕，因此用藥規律上虛證與實證用藥頻率依據臨床症候有所差別。其中使用頻數超過13次的藥物功效主要是利水滲濕藥、補虛藥、溫裏藥、收澀藥。超過用藥頻次13次的前十二味藥物中，入腎經的藥物佔七味。結論：本研究發現傅青主男科治療男性不孕症用藥特點以健脾補腎藥為主，同時使用清熱、化痰祛濕、疏肝、理血藥以達到重視調理先後天之本，少用攻邪耗散藥，顧護正氣。期盼本文對臨床中醫在治療男性不孕症能有所助益。至於其藥理作用機理仍日後有待更進一步探討。

Objective: To explore the characteristics of formulas used to treat male infertility in Fu Qingzhu's Medical Department for Men and to analysis it. Also connect to modern Chinese medicine view in the male infertility. Material: In our study, we mainly used Fu Qingzhu's Medical Department for Men to discuss the medication rules and frequency of male infertility. Method: All prescription medication for male infertility were used for statistical analysis, including the frequency , the function and the classification of it. Results: There are 81 Chinese medicine used in Fu Qingzhu's Medical Department for Men. All of them were used up to 450 times. The pathogens of male infertility were due to kidney deficiency, liver stagnation, blood deficiency, blood stasis, and phlegm in Chinese medicine view. Above them, the Chinese medicine which were used more than 13 times is mainly for diuresis, dampness, warmth, and astringent medicine. Among them, which were used more than 13 times, are classified in kidney in Chinese medicine's view. Conclusion: The study found that the treatment in Fu Qingzhu's Medical Department for Men of male infertility is mainly based on spleen and kidney. At the same time, he used heat-clearing, phlegm-removing, damp-relieving, liverdrenching, and blood-conditioning drugs to achieve the balance. We hope this article will be helpful for clinical TCM in treating male infertility. As for its pharmacological action mechanism, it still needs to be further explored in the future.