標靶藥物、免疫治療、生物製劑的前眼部副作用

The Side Effects of Target Therapy, Immunotherapy, and Biologics on External Eye

如同前面的文章所提及，標靶藥物、免疫治療、生物製劑雖然帶來許多治療新契機，但其全身性治療卻亦會造成眼部方面許多副作用。「前眼部」由於其特殊生理及結構，也會受到這些藥物的影響。在此，我們將會討論這類新穎的治療如何造成「前眼部」的副作用，及其臨床上的處置。

Over the past decades, there has been an increase in the use of novel treatment options such as targeted therapy, immunotherapy and biologics, particularly in oncology practice. Although these agents are thought to be more specific and less toxic than traditional cytotoxic chemotherapy, they are associated with a variety of toxicities, including ocular side effects due to their specific targeting activities in the eye. In this article, we discussed the proposed pathogenesis, monitoring guidelines, and management recommendations for the adverse events of these agents on external eye. Collaboration between oncologists and ophthalmologists is essential to diagnose and treat these side effects promptly.