比較良性攝護腺肥大患者二種治療方式之生活品質

A Comparative Study of the Quality of Life on Two Different Yupes of Therapy for BPH Patients

本研究目的藉由治療成功率當做臨床治療結果指標、及生活品質當做以人道關懷結果指標，做整體性評估，以比較攝護腺肥大患者接受口服藥物與手術二種不同治療方式，在治療六個月後療效結果之差異性。採類實驗設計法的二組前後測設計，以攝護腺肥大健康相關生活品質量表及國際攝護腺症狀評分表(IPSS)（治療成功定義：治療六個月後達到降低IPSS30%）為研究工具。研究期間自民國90年11月至91年4月，採立意取樣法，研究對象是臺北市某醫學中心，在門診期間被醫師診斷為中度阻塞症狀之攝護腺肥大患者，一組為未接受手術而使用同一種藥物治療，另一組為願意接受手術。治療6個月後，以相同方式請個案填寫第二次攝護腺肥大之健康相關生活品質量表及國際攝護腺症狀評分表；二組各100人回門診填答問卷，回收率100%。研究結果發現，接受手術治療或口服藥物治療6個月後之生活品質及IPSS分數皆比治療前顯著改善，接受手術治療6個月後之生活品質與口服藥物治療6個月後之生活品質改善程度無顯著差異；雖然手術治療6個月後在國際攝護腺症狀評分(IPSS)較口服藥物治療有顯著進步，但成功率卻無顯著不同。根據研究結果，期望能提供醫療人員做決策時之參考，以做為提升攝護腺肥大病患生活品質之依據。

The purpose of this study is using treatment successful according to clinical outcoome and using life quality according to humanistic outcome for total evaluation to compare the difference between life quality on benign enlarged-prostate patient who has been treated by oral medicine or surgery. This study was a quasi- experimental design to explore the effects on life quality between the two different treatments. The reliability and validity-tested instruments were used in this study as followings: the patient?s questionnaire about life quality and International Prostate Symptom Score,IPSS(the definition of successful is to fall IPSS 30%). During November of 2001 to April of 2002, a total of 200 samples that were diagnosed as mid-level clog enlarged prostate were drawn from outpatient clinic in a Taipei medical center. There were two groups in this study; 100 patients were included in oral medicine treatment (used the same medicine), and another 100 were treated by surgery.After treating for six mons,we let patients anser the questionnaire about life quality and IPSS for the second time.There are 100 people in each two groups coming back to the opd to anser the questionnaire.The collecting rate can approach to 100%. According to this study, the results stated that the surgery patients and oral medicine treatment had much more progress than before treatment on the life quality and IPSS. There was no notable difference on life quality between the groups after six months. Surgery patients had much more progress than oral medicine treatment on the IPSS. But no notable difference on successful between the groups after six months. The results of this study may offered an important reference to the hospital administrators and nurses who dedicated decision-making and quality care to the service.