從一位HIV患者感染Ciprofloxacin抗藥型B型志賀氏菌之鑑定探討臨床實驗室鑑別志賀氏菌之挑戰

Identification of a Ciprofloxacin-resistant Shigella flexneri from a patient with HIV infection - the challenge of laboratory diagnosis

志賀氏症是一種急性腸胃炎，主要經由糞口途徑傳播。臨床感染志賀氏菌機率較高者為免疫抑制的患者，及由男同性戀者引起的病菌散播和群聚突發性感染。在此我們呈現一位人類免疫不全症候群男性患者感染B型志賀氏痢疾的鑑定案例，來探討臨床實驗室之鑑定工具用於鑑別志賀氏菌及大腸桿菌技術面的限制與挑戰。

Shigellosis is an acute gastroenteritis, which is transmitted by the fecal-oral route. The risk of Shigella has been shown to be higher in immunocompromised patients. Shigellosis can also be a sexually transmitted infection in men who have sex with men (MSM) to cause outbreaks and circulation in shigellosis low-risk regions. Here, we present a case of Shigella flexneri dysentery in a patient with HIV infection, to investigate the challenge of conventional laboratory techniques versus automated identification systems in differentiating between Shigella species and Escherichia coli.