The establishment of the Taiwan nurse practitioner (NP) role is an important milestone for Taiwan’s medical business development in the past decade. It is also considered the most effective solution for the medical manpower shortage in Taiwan. In this article, the development process of the trauma NP role and function in the Emergency Medicine Department of a public medical center in Kaohsiung is described. The contents cover trauma NPs’ practice scope, job description, clinical training, continued education, and future outlook. The information described is aimed to provide a reference for the future development of NP and medical manpower in Taiwan.