以雄性SD大鼠模式評估桂格養氣人蔘雞精之抗疲勞效用

Evaluation of Quaker Essence of Chicken with American Ginseng on Anti-fatigue Function in Male SD Rat Model

本研究主要調查在SD大鼠模式下桂格氧氣人蔘雞精是否具抗疲勞效用。十六隻大鼠分成控制組與實驗組，每組各八隻，控制組服用2mL/kg的蒸餾水。實驗組餵食1.13mL/kg桂格氧氣人蔘雞精六週。另外16隻大鼠重複上述試驗，但餵食桂格氧氣人蔘雞精八週。實驗結束時以游泳試驗紀錄老鼠力竭時間。實驗過程中無老鼠死亡，實驗過程中身體與行為檢查皆未發現任何異常。實驗結果無論餵食六週（227±153min）或八週（153±64min），游泳力竭時間皆顯著延長。然而肝醣卻未因為服用桂格氧氣人蔘雞精而增加。結果證明桂格氧氣人蔘雞精具抗疲勞效用。

The aim of this study was to investigate whether Quaker Essence of Chicken (with American Ginseng) has an anti-fatigue effect in SD rats. Sixteen Rats were randomly divided into 2 groups, each containing 8 animals. The control group received 2 mL/kg body weight of distilled water. The treated swimming groups were administrated Quaker Essence of Chicken liquid at doses of 1.13 mL/kg body weight for a period of 6 weeks treatment. Another 16 rats were repeated the above experiments but for a period of 8 weeks treatment. At the end of experiments, rats were made to perform swimming exercise and the total swimming time until exhaustion was measured. No mortalities occurred during the study. Physical and behavioral examinations did not reveal any treatment-related adverse effects after dosing. Both six-week (227± 153 min) and eight-week (153±64 min) treatment groups showed a significant increase swimming time to exhaustion in comparison to control groups. After swimming, liver glycogen did not increase by the treatment of Quaker Essence of Chicken liquid when compared with control groups. These results suggest that Quaker Essence of Chicken liquid improves swimming endurance and has an anti-fatigue effect.