母親於哺乳期中藥食療之新生兒健康評估

Healthy Evaluations of Breastfed Infants in Maternal Consumption with Chinese Herb-Enriched Diet

在許多國家，有非常多的婦女在生產後服用中藥。但母親服用這些中藥的同時又哺餵母乳，是否會對嬰兒造成影響，目前卻無人研究。本研究評估母親於哺乳期中藥食療與嬰兒健康之關聯性，研究對象為哺餵母乳之嬰兒，年紀為25至45天大，共收案420位嬰兒。結果顯示，比起母親沒有服用四物湯加減﹙modified Si-wu-tang﹚之嬰兒，母親服用四物湯加減之嬰兒較少有黃疸﹙p=0.001﹚。母親服用麻油雞之嬰兒有較頻繁之大便次數﹙p=0.004﹚。母親於產後曾併用四物湯加減、麻油雞、杜仲、生化湯者有較少之黃疸﹙p<0.001﹚及較多之大便次數﹙p=0.039﹚。母親服用中藥與嬰兒生長並無關連。多變相邏輯式回歸模式分析結果顯示母親服用四物湯加減之嬰兒較少有黃疸，母親服用麻油雞之嬰兒有較多之大便次數。本研究結論為母親中藥食療與嬰兒健康有關聯性，結果認為母親於哺乳期中藥食療對嬰兒健康是安全的，母親於產後服用四物湯加減可考慮為降低母乳性黃疸之一個另類療法。

Chinese herbs are traditional diet for postpartum women in many countries. However, the potential impact of maternal consumption with Chinese herb-enriched diet on nursing infants has not been well investigated. Our objective was to identify the association between health of breastfed infants and maternal diet with Chinese herbs. A total of 420 infants with exclusively breastfeeding at 25 to 45 days of age were enrolled into this prospective study. There was a decline of jaundice in infants of maternal diet with modified Si-wu-tang when compared to those without modified Si-wu-tang (p < 0.001). In addition, infants of maternal diet with sesame oil chicken more often defecated (p = 0.004). A combination of maternal consumption with modified Si-wu-tang, Sheng-hau-tang, Eucommia ulmoides, and sesame oil chicken was related to a decline of jaundice (p < 0.001) and an increase of stool passage (p = 0.039). There was no significant correlation of maternal diet with infant growth. The multivariate logistic regression analysis demonstrated greater risk of frequent stooling at maternal diet with sesame oil chicken and lower risk of jaundice at maternal diet with modified Si-wu-tang. In conclusion, there is a relationship between maternal consumption with Chinese herb-enriched diet and infant health at age of one month. The results suggest maternal intake with Chinese herb-enriched diet is safe for nursing infants. Maternal diet with modified Si-wu-tang may serve as an alternative strategy to prevent breast milk jaundice.