After implementation the global budget of the National Health Insurance in order to reduce the hospital’s high rising expenditure, job stress was increased among medical workers. This study was to investigate stress at work among Chinese medical doctors and dentists and their factors during the implementation of the global budget payment system. A questionnaire survey with a stratified and proportional random sampling in Taoyuan was used to obtain the sample. Questionnaire on medical workers stress(QMWS) with acceptable reliability and validity was used. From July to December 2006, 81 valid questionnaires were obtained (51 Chinese medical doctors, 30 dentists). The total score of the QMWS was 15.73±6.57 and the percentile was 37.5. Two individual scores of QMWS (running a hospital, and paying employee’s salary) were significantly worse for Chinese medical doctors than those for dentists. Satisfaction with their salaries was as high as 70.4%. Category of doctor were significantly associated with the QMWS, explaining 8.9% variation of QMWS. During the global budget payment system, Chinese medical doctors had higher occupational stress than dentists did, especially running a hospital, and paying employee’s salary. Most of them were satisfied with their pay.