台灣停經前期女性子宮肌瘤盛行率與身體質量指數和腰圍的相關性研究

The Relationships between Uterine Myomas, Body Mass Index and Waist Circumference of Premenopausal Women in Taiwan

背景及目的：子宮肌瘤是停經前期女性常見的婦科問題之一。本研究旨在了解台灣婦女子宮肌瘤盛行率，子宮肌瘤和體重過重與中心性肥胖的相關性。
方法：本研究以北部某健康檢查中心之調查問卷及該次檢查結果為工具，以婦科超音波診斷為依據，使用多變項邏輯迴歸了解子宮肌瘤和各變項之相關性。
結果：符合資料完整納入分析條件的停經前期婦女有5,842人，平均年齡為43.9 ± 2.3歲，平均身體質量指數為21.9 ± 2.8 kg/m2，其中有2905位(49.7%)有子宮肌瘤，發現子宮肌瘤盛行率隨者年齡增加而增加，約有六成46-48歲台灣婦女患有子宮肌瘤。有子宮肌瘤者，年齡較高、吸菸比例較高、運動習慣比例較少、身體質量指數較大與腰圍較粗。再將以上變項與子宮肌瘤進行邏輯迴歸分析，發現和體重過重 (OR=1.217; 95% CI＝1.014 - 1.461)，肥胖 (OR=1.322; 95% CI＝1.007 - 1.755)，腰圍(OR=1.016; 95% CI＝1.007 - 1.026)，達中心型肥胖 (OR=1.201; 95% CI＝1.024 - 1.410)呈現正相關。
結論：近5成停經前期婦女有子宮肌瘤，確是常見疾患，且肥胖的婦女較正常體重者增加32%得到子宮肌瘤的風險，中心性肥胖者得到子宮肌瘤的風險增加20%，並達統計上顯著相關。

Background and Purpose: Uterine myomas are one of the most common gynecological disorders in premenopausal women. The purpose of this study is to investigate the prevalence of uterine myomas among women in Taiwan and the relationships between uterine myomas, overweight, and central obesity.
Methods: Questionnaires and test results from routine checkups performed at a health care center in northern Taiwan were collected and gynecological sonography used to diagnose uterine myomas. Utilizing SPSS software, the study analyzed data based on a logistic regression model to investigate the relationship between uterine myomas and other variables.
Results: A total of 5,842 premenopausal women enrolled in the study, reporting an average age of 43.9 ± 2.3 years and an average body mass index of 21.9 ± 2.8. 2,905 (49.7%) of the women had uterine myomas. The prevalence of myomas increased with age, as indicated by our detection of myomas in approximately 60% of the Taiwanese women aged 46 to 48 years old. The women in the myoma group tended to be older and were more likely to smoke, exercise less, and show a higher body mass index and a greater waist circumference. The logistic regression results identified a positive association with uterine myomas in overweight (OR = 1.217 ; 95% CI = 1.014 - 1.461), obesity (OR = 1.322; 95% CI = 1.007 - 1.755), central obesity (OR= 1.201; 95% CI=1.024 - 1.410) and greater waist circumference (OR= 1.016; 95% CI=1.007 - 1.026).
Conclusions: Almost half of the premenopausal women in Taiwan had uterine myomas, testifying to the status of uterine myomas are a common disorder. Obese premenopausal women had a 32% greater risk of developing uterine myomas than their non-obese counterparts. Central obesity increased the risk of uterine myomas by 20% with statistically significant evidence.