The purpose of this study was to determine whether the breastfeeding problems of Taiwanese and American mothers differed at 3 weeks postpartum, as measured by the Breastfeeding Experience Scale (BES). Methods: Seventy-two Taiwanese and 55 American Primiparae who had experienced spontaneous vaginal deliveries completed two questionnaires: one to record socio-demographic characteristics and the other for self- report of breast-feeding problems – the Breastfeeding Experience Scale (BES) (higher scores on the BES indicated more concerns in a particular dimension). Results: Taiwanese mothers had higher scores on the BES items “worry baby was not getting enough milk” (p <0.02, χ2), “worry about baby’s weight gain” (p <0.007, χ2), and “difficulty combining work and breastfeeding” (p <0.001, χ2). American mothers had higher scores on the “sore nipple” (p < .0001, χ2) and “feeling tense and overwhelmed” (p<0.003, χ2) BES items compared to the Taiwanese mothers. Conclusion: These results suggest that differences exist in the breastfeeding experiences of Taiwanese and American women. More detailed descriptive studies should be conducted to identify the causes and possible culturally sensitive health care interventions to address early breastfeeding problems.