Background: Oral mucositis is a common complication after chemotherapy, radiation therapy. Oral mucositis will impact the desire appetite, decrease nutrient intake, and impede tissue repair.
Purpose: This study was a systematic review. The purpose was to compare the effectiveness of different mouthwash solutions in organ transplantation patients. The relationships among mouthwash solution with incidence, severity, and duration of oral mucositis were analyzed.
Methods: Literatures were searched from electronic database of CEPS, PudMed, Cochrance library, and Medline. Keywords including "oral mucositis" or "Stomatitis" and "transplantation" and "mouthwash" were keyed in, and 45 articles were extracted. Finally, 17 articles selected for further analysis after excluding repeated topics.
Results: The mouthwash solution for transplant patients included Chlorhexidine, Glutamin, Povidoneiodine, Nystatin and folic acid. Chlorhexidine is the most effective mouthwash solution.
Conclusions / Implications for practice: Transplant patients using Chlorhexidine can significantly reduce the incidence and severity of oral mucositis. Results of this review suggests Chlorhexidine mouthwash solution is the priority choice for transplant patients.