This study analyzed the prescription patterns of Chinese herbal products (CHPs) in patients with psoriasis based on outpatient service data of National Health Insurance Research in Taiwan and investigated their clinical application. This population-based cohort study was conducted using a randomly sampled cohort of one million patients between 2003 and 2013 selected from the National Health Insurance Research Database in Taiwan. The use of CHPs and the top ten most frequently prescribed formulae and single herbs for treating psoriasis were assessed, including average formula doses and frequency of prescriptions. Demographic characteristics including sex and age were examined. The therapeutic principles and possible mechanisms of CHPs prescriptions are discussed. We identified 1,055 (8.5%) patients with psoriasis who used CHPs during the study period. Patients between 19 and 45 years of age comprised the largest number of those treated (54.6%). Male patients used CHPs forpsoriasis more frequently than did female patients (male:female = 1.4:1). The most frequently prescribed herbal formula and single herb for the treatment of psoriasis were Wen-Qing-Yin and Mu Dan Pi, respectively. According to the association rule, the most commonly prescribed twoformula CHP combination for treating psoriasis was Wen-Qing-Yin plus Xue-Fu-Zhu- Yu -Tang, while the most commonly prescribed combination of formula CHP and single herb was Xiao-Feng-San plus Tu Fu Ling. Further research is required to fully elucidate the efficacy and safety of these CHPs.