巴金森氏症病人症狀及緩和治療相關因素之研究

Symptoms and Palliative Care-Related Factors in Patients with Parkinson's Disease

巴金森氏症是一種漸進性的中樞神經退化疾 病，然而因病程時間長，且病人長期受功能減退與 各項症狀困擾，顯著影響其生活品質，但其緩和醫 療利用率卻僅0.6％。本研究目的在探討巴金森氏症 病人症狀與緩和治療的相關因素，期能提供病人更 好的照護。 ݲП 本研究採用橫斷式相關性研究設計，以立意取 樣法，共收集64位符合收案條件者：一、診斷為 原發性巴金森氏症病人；二、神智清楚、無精神疾 病、失智症等疾病；三、經解釋研究目的後，同意 參與研究者。量表包括：緩和療護巴金森氏症症狀 量表（Palliative Outcome Scale-Parkinson Disease, POS_PD）及緩和療護結果量表（Palliative Outcome Scale, POS）。以SPSS 19.0版進行資料分析，統計 方法包括獨立樣本t檢定、單因子變異數分析及迴歸 分析。 ݎ๖ 由看護照顧者、H&Y侯葉分級較高、有去過急 診者，有顯著較高的緩和療護需求，亦代表生活品質 較差；巴金森氏症症狀與緩和療護結果間呈中度正相 關（r=0.65, p

Purposes Parkinson's disease (PD) is a progressive degenerative disease of the central nervous system. It significantly affects patients' quality of life due to the long disease course, longterm dysfunction, and various symptoms. In addition, the palliative care utilization rate is only 0.6%. The purpose of this study was to explore the factors related to the symptoms and palliative treatment of patients with PD, so as to provide better care for patients. Methods This study employed a cross-sectional correlational study design, and purposive sampling was used to enroll 64 participants. The inclusion criteria for patients were: (1) diagnosis with primary PD disease; (2) clear mental state, free from psychiatric diseases and dementia; and (3) provision of informed consent after the aim of the study was explained to him/her. A set of validated instruments, including the Palliative Outcome Scale-Parkinson Disease (POS-PD) and Palliative Outcome Scale (POS), were used for data collection. SPSS 19.0 software was used for data analysis. The statistical methods included an independent sample t-test, one-way analysis of variance, and regression analysis. Results Subjects with caregivers, higher Hoehn and Yahr stage or those who visited the emergency department had a significantly higher need for palliative care, which also represents a poor quality of life. PD symptoms showed moderate positive correlation with palliative care outcomes (r=0.65, p