原發性陰道惡性黑色素瘤：案例報告與文獻回顧

Primary Melanoma of vagina: a case report and review of the literature

原發性陰道惡性黑色素瘤是極為罕見，經常較晚期才被發現及診斷、惡性度高、易復發轉移，導致對手術治療、放射治療、化學治療等治療效果及存活率均不佳。迄今為止有關原發性陰道惡性黑色素瘤該採取何種治療方式，以提高其治療效果及預後仍未有明確共識。本案例報告，就是在分享一位原發性陰道惡性黑色素瘤的病患其相關診斷、治療及後續追蹤的狀況。

Primary malignant melanoma of the vagina (PMV) is extremely rare, accountingfor less than 3 % to all vaginal cancers. In women, only 1.6 % of melanomasare genital origin. The most common site is the vulva (70 %), followed by thevagina (21 %) and the cervix (9 %). The incidence of PMV is only 0.46 per onemillion women per year and with only around 800 cases reported in the literatureto date. The most common presenting symptoms include vaginal bleeding,vaginal discharge, and vaginal mass. Vaginal melanoma is often detected late,and this may be the most responsible for poor treatment outcomes and survivalrates. To date there is no clear consensus regarding treatment due to the rarity ofvaginal melanoma.