全身性糖皮質類固醇於成人加護病房之使用現況

The Use of Systemic Glucocorticoids in Intensive Care Units

臨床上糖皮質類固醇被廣泛地應用於治療各種疑難雜症，減輕許多症狀的嚴重程度，使病情獲得緩解。20世紀初研究人員觀察到，腎上腺在人體面臨壓力時對生存至關重要，便對糖皮質類固醇於重症疾病中的病理生理學角色產生興趣。在成人加護病房的用藥中，全身性糖皮質類固醇是最常使用的藥物之一，其扮演的角色一再被探討著。儘管在現代重症醫學的照護實行中仍是一個具有爭議的領域，本篇整理了一些最新的臨床指引及文獻證據，提供醫療專業人員正確地使用全身性糖皮質類固醇，以提升病人用藥安全。

Glucocorticoids are widely used in the treatment of various diseases. They alleviate many symptoms and make them relieved. Interest in the role of glucocorticoids in the pathophysiology of critical illness has existed since the early part of the 20^(th) century, when investigators observed that the adrenal glands are crucial to survival under conditions of physiologic stress. Glucocorticoids are one of the most common medications that are used for a variety of indications in the intensive care units, and its role has been explored and discussed continuously. This article has compiled some of the latest clinical guidelines and documentary evidence to provide medical professionals with the correct use of systemic glucocorticoids, although there is still a controversial area of modern critical care practice.