實驗室調查ceftazidime-resistant Haemophilus parainfluenzae的群聚感染

A Cluster Infection of Ceftazidime-resistant Haemophilus Parainfluenzae

At a regional hospital in southern Taiwan, three strains of ceftazidime-resistant Haemophilus parainfluenzae were isolated from three different patients between 9 May 2014 and 6 June 2014. Reconed as a rare phenomenon, an outbreak investigation was implemented. Pulsed-field gel electrophoresis (PFGE) was performed for genotyping of the bacterial strains. Results revealed these three strains were derived from different origins, indicating this was a cluster infection rather than an outbreak. Herein, it is still highly suggested that under an outbreak possibility, a molecular investigation should be implemented, especially encountering of different strains of the same species of antibiotic-resistant organisms isolated. 在南台灣的某家區域醫院，在2014年5月9日到6月6日，在三位不同病患分離出三株對ceftazidime產生抗藥性的Haemophilus. parainfluenzae，因為這是一種不尋常的現象，因此展開群突發調查。使用脈衝式電泳分析法（pulsed-field gel electrophoresis；PFGE）做菌株比對，結果顯示這三株細菌是不同的菌株，因此，這只是一個群聚感染，而不是群突發。在此我們仍然高度建議，一旦發現某種抗藥性細菌突然增加，必須高度懷疑發生群突發的可能性，並展開群突發的調查。