肥胖與第二2型糖尿病（T2DM）之間的聯繫

The Link between Obesity and Type 2 Diabetes Mellitus

Obesity remains one of the main variables associated with type 2 diabetes mellitus (T2DM), originally known as adult-onset diabetes, which influences the efficiency of metabolizing glucose-the essential energy source for the body. T2DM, furthermore, causes an increase or reduction in insulin production. Insulin resistance happens when the use of insulin is restricted. Obesity, a critical risk factor, increases the impacts of T2DM resulting in liver diseases and pancreatitis. The lack of muscle mass has also become another risk factor for the onset of T2DM, making it difficult for the body to efficiently use glucose. Excess levels and thus increased accumulated fat in the body changes the way in which it responds and reacts to insulin. 肥胖仍然是與第二型糖尿病相關的變數之一。第二型糖尿病已被確定為成人發病型糖尿病，葡萄糖是人體必需的能量來源，如何使用葡萄糖其方式對於第二型糖尿病患者有著極大的影響。此外，第二型糖尿病的特徵在於胰島素產生抵抗或胰島素相對缺乏時所造成的高血糖，當身體限制胰島素的使用時，就會導致胰島素抵抗。肥胖是一個關鍵的危險因素，它會刺激體內的免疫反應使得患者的血糖升高將其將會增加第二型糖尿病患罹患肝病和胰腺炎。肌肉量減少也成為第二型糖尿病發病的獨立危險因素，這將使得體內處理在葡萄糖時帶來麻煩。過量的脂肪增加了人體的負擔，改變了它對胰島素的反應方式。