輕度行為障礙：失智症前驅症狀新觀點

Mild Behavioral Impairment: A New Concept of Prodromal State of Dementia

全球失智症人口逐年上升，而神經精神症狀（neuropsychiatric symptoms，NPS）是失智症家屬的主要負擔來源，亦常出現在失智症的前驅期。「輕度行為障礙」（mild behavioral impairment, MBI）是失智症前驅症狀的新觀點，其定義為50歲以後才發生的行為或個性改變，症狀持續超過6個月的時間，並且至少輕微影響功能。目前，已有專為MBI設計的量表，相關的實證資料亦逐漸增加，其在科學與臨床實務的價值需進一步研究。 he prevalence of dementia is increasing by years. Neuropsychiatric symptoms of dementia are the major source of burden to family and frequently observed in the prodromal or pre-clinic state of the dementia. Mild behavioral impairment (MBI) is a new concept of the prodromal or pre-clinic state of the dementia. Its diagnostic criteria include behavioral or character change onset after 50 years old, symptoms persisting for more than 6 months, and at least minimal functional impairment. Flourishing studies are aimed at MBI recently, including a checklist specially developed to measure it. The value of this new concept is worthy of expectation in terms of the scientific research and clinical practice.