氣相層析質譜法分析尿液中天使塵之實驗室共同研究   全文下載

Collaborative Study on the Determination of Phencyclidine in Urine by Gas Chromatography-Mass Spectrometry

本研究將尿液中天使塵分析的氣相層析質譜法應用於實驗室共同研究。實驗室之共同研究乃依據國際分析化學家協會所建議之方式進行，共有10家台灣的濫用藥物尿液檢驗實驗室參與，分析3 組二重複的檢體，各實驗室間尿液中天使塵的RSDr 及RSDR 分別為於2.1%-3.6% 與4.2%-7.3%，其HORRAT 值介於0.4-0.7，顯示本方法在實驗室內及實驗室間均具良好的精確性。這些數值顯示本分析方法在各濫用藥物尿液檢驗實驗室間具良好之再現性，未來可作為檢驗實驗室分析尿液中天使塵的參考。

A gas chromatography-mass spectrometry method for the analysis of phencyclidine (PCP) in urine was subjected to an interlaboratory study. The collaborative study followed the guidelines provided by the Association of Official Analytical Chemists International. Ten laboratories participated, analyzing 3 samples of PCP-spiked urine as blind duplicate. The repeatability relative standard deviation (RSDr) and the reproducibility relative standard deviation (RSDR) were between 2.1%-3.6% and 4.2%-7.3%, respectively. HORRAT values for the reproducibility showed 0.4-0.7, indicating acceptable precision between laboratories. The method was thus proposed to be used by the drug-abuse urine testing laboratories in Taiwan.