奈米碳管修飾網版印刷電極分析化妝品中麴酸   全文下載

Flow Injection Analysis of Kojic Acid in Cosmetics by a Carbon-Nanotube Modified Screen-Printed Electrode

研究發現將新式的奈米碳管網版印刷電極（Cnt/SPE）應用至流動注入分析法時具有高度價值。影響分析物在電極上氧化程序的變因包括：pH、施加電位、流速、奈米碳管的塗佈量等，在本研究中皆被深入探討。最佳條件下，於濃度範圍0.1-120 ppm的校正曲線實驗，顯現良好線性關係，偵測極限（S/n = 3）可達0.01 ppm，相對於一般未修飾之網版印刷電極（SPE），Cnt/SPE在麴酸分析時提供更高的感應靈敏度。研究結果顯示出Cnt/SPE具有優良的穩定度與再現性，揭示其未來在液相層析系統的應用潛力。以分批製備的五組 Cnt/SPE對20 ppm麴酸樣品進行分析，由結果rSd值 4.43%可知本研究之電極製備程序具良好再現性。最後，對含麴酸化妝品分析的可靠結果，證明本系統可作為化妝品中麴酸成份檢測之利器。

A novel carbon-nanotube modified screen-printed electrode (CNT/SPE) was successfully prepared and validated to be a useful detector in the flow injection system. Compared to a bare screen-printed electrode (SPE), CNT/SPE improved the detection limit for kojic acid (KA). The detection limit on S/N = 3 was as low as 0.01 ppm. Furthermore, several factors, including the pH, applied potential, flow rate and coating quantity of CNT, were assessed. The attractive response of CNT/SPE has allowed it to be used for constant-potential FIA (Flow-Injection Analysis) of KA and indicates great potential for monitoring chromatographic effluents. The linear relationship between KA concentration (0.1-120 ppm) and the current response was established. Meanwhile five different CNT/SPEs for the detection KA of 20 ppm yielded a RSD value of 4.43%, indicating acceptable reproducibility of the present analysis. Finally, two real samples on the market were analyzed using the proposed system with appreciable results.