超臨界流體於中草藥之應用－－由製備到分析   全文下載

An Overview of Supercritical Fluid Extraction in Chinese Herbal Medicine: from Preparation to Analysis

本文回顧文獻中超臨界流體於中草藥的萃取及分析之應用，預料應用超臨界流體於中草藥產品之製備會愈來愈廣泛。文中並逐一探討有效成分之製備及有害成分之分析的應用實例。超臨界二氧化碳流體具有多種優點，有取代傳統萃取溶劑的趨勢，配合次臨界水的使用，可應用於更多種類的中草藥，同時具有萃取有效成分及去除有害成分的雙重功效。若能有效的整合實驗室結果應用於中草藥產品量產工廠的設計及生產，將有助於使超臨界流體萃取成功的應用於中草藥。

A review concerning the use of supercritical fluid extraction (SFE) in the preparation and analysis of Chinese herbal medicine (CHM) is presented. The literature review foresees the trend of increasing use of SFE in CHM preparation. The application examples in the preparation of useful ingredients and analysis of pesticide residues are discussed. The use of SFE CO2 to replace traditional organic solvent is justified and promising. Consideration is given to the coupling of sub-critical H2O and supercritical CO2 to extract more compounds and to use the dual role of extracting useful ingredients and removing pesticide residues. Careful integration of laboratory SFE results into the design and implementation of factory production is beneficial in ensuring the successful use of SFE in CHM. 本文回顧文獻中超臨界流體於中草藥的萃取及分析之應用，預料應用超臨界流體於中草藥產品之製備會愈來愈廣泛。文中並逐一探討有效成分之製備及有害成分之分析的應用實例。超臨界二氧化碳流體具有多種優點，有取代傳統萃取溶劑的趨勢，配合次臨界水的使用，可應用於更多種類的中草藥，同時具有萃取有效成分及去除有害成分的雙重功效。若能有效的整合實驗室結果應用於中草藥產品量產工廠的設計及生產，將有助於使超臨界流體萃取成功的應用於中草藥。