中藥材品質調查(II)   全文下載

Investigation of the Quality of Chinese Herbs (II)

本調查於台北地區價購川牛膝、桔梗、香附、當歸、薏仁、杏仁、白茯苓、白芷、枸杞、川芎、杜蠣、天花粉、杭菊花、荊芥、桑白皮、川楝子、玄參、甘草、何首烏、浙貝母、防風、鬱金、益母草、麥門冬、綿茵陳、連翹、山藥、銀花、陳皮、桃仁等三十種中藥材，每種藥材各20件，計600件之檢體，就乾燥減重、總灰分、酸不溶性灰分、稀醇抽提物及水抽提物等項目試驗。其中甘草藥材同時就指標成分glycyrrhizin含量予以測定。另亦透過台灣區製藥公會會員廠，搜集各中藥廠依本調查之各項分析方法檢驗並提供上述三十種藥材相關實驗數據，再加上彙集文獻中相關之檢驗資料一併歸納整理。綜合以上結果，三十種藥材中，每種藥材各檢體之五項試驗結果，與其M±S.D．值比較，其乾燥減重、總灰分、酸不溶性灰分之三項試驗值分佈低於其M±S.D．者，稀醇抽提物、水抽提物之試驗值分佈高於其M-S.D．者，尚屬分佈於合理範圍之藥材，包括川牛膝、桔梗、薏仁、白芷、麥門冬、綿茵陳及銀花等七種中藥材。其餘包括香附等二十三種中藥材，每種藥材均有一至三項之試驗結果超出或低於其M±S.D．值之檢體數超出合理範圍。本實驗以此等數據為藍本，以統計學原理訂定一涵蓋多數合理之數據，作為上述三十種藥材各項試驗之建議值，以供參考。

In this investigation, thirty kinds of marketed Chinese herbs including Cyathula Capitatae Radix, Platycodi Radix, Cyperi Rhizoma, Angelicae Sinensis Radix, Coicis Semen, Armeniacae Semen, Poria, Angelicae Dahuricae Radix, Lycii Fructus, Ligustici Wallichii Rhizoma, Ostreae Testa, Trichosanthis Radix, Chrysanthemi Flos, Schizonepetae Herba, Mon Radicis Cortex, Meliae Toosendan Fructus, Scrophulariae Radix, Glycyrrhizae Radix, Polygoni Multiflori Radix, Fritillariae Thunbergii Bulbus, Ledebouriellae Radix, Curcumae Tuber, Leonuri Herba, Ophiopogonis Tuber, Artemisiae capillaris Herba, Forsythiae Fructus, Dioscoreae Rhizoma, Lonicerae Flos, Citri Leiocarpae Exocarpium, Persicae Semen were analyzed.Analyses of loss on drying, diluted ethanol-soluble extractive, water-soluble extractive, total ash and acid-insoluble ash of herbs were carried out. In addition, the marker constituent, glycyrrhizin in Glycyrrhizae Radix was also analyzed.To summarize the above survey results of the five tests done for each herb, the produced values compared with their M+S.D.or M-S.D., seven herbs that displayed a reasonable distribution in their test results included Cyathula Capitatae Radix, Platycodi Radix, Coicis Semen, Angelicae Dahuricae Radix, Ophiopogonis Tuber, Artemisiae capillaris Herba and Lonicerae Fbos. The other twenty-three herbs showed that one to three of the five tests carried out displayed an unreasonable distribution. Based on the data obtained, this experiment is able to generate a statistic value that can cover most of the reasonable data. These data then can serve as a remarkable estimation values for the future testing on the above thirty herbs.