SiO2-AITC抗菌粒子製備條件之探討

Study on Preparation of the AntimicrobialSiO2-AITC Particles

市面上有許多具有抗菌成分的包裝材料，可以保持食品的新鮮度。本研究使用二氧化矽吸附異硫氰酸烯丙酯，製備成SiO2-AITC抗菌粒子，探討SiO2-AITC抗菌粒子在製備過程中不同乾燥條件及粒徑大小對AITC釋放量之影響，三種不同乾燥條件（-20℃冷凍乾燥、35℃真空乾燥及75℃真空乾燥）製備SiO2-AITC抗菌粒子時，以35℃真空乾燥所製備之SiO2-AITC抗菌粒子的釋放量（19.60±0.06μL/g）最多，另外，粒徑大小也會影響SiO2-AITC抗菌粒子的釋放量，結果顯示出<25 μm粒徑之抗菌粒子，是三種不同大小粒徑（44-75 μm、25-44 μm和 < 25μm）中具有最佳的釋放量（19.60±0.06μL/g; P<0.05）。使用<25μm粒徑的二氧化矽在35℃真空乾燥條件下製備SiO2-AITC抗菌粒子，貯存在高溫高濕度（38℃；98%RH）環境下第一天具有最快的釋放率（89%）。未來可將SiO2-AITC抗菌粒子添加至食品包材中，讓包裝袋內的天然抑菌物質釋放出來，抑制食品表面的微生物，以延長食品的保存期限。

There are many antimicrobial packaging materials available on the market that can keep food fresh. In this study, the antimicrobial SiO2-AITC particles were prepared by drying after absorption of AITC to SiO2. The effects of different drying processes and particles sizes on the release of AITC were investigated. Among three drying processes (-20℃freeze-drying, 35℃vacuum drying and 75℃vacuum drying), the SiO2-AITC particles prepared by the 35℃vacuum drying obtained the highest release of AITC (19.60 ± 0.06 μL/g). Among three particle sizes (44-75 μm, 25-44 μmand <25μm) produced, the smallest SiO2-AITC particles (<25μm) provided the most significant release of AITC (19.60 ± 0.06 μL/g; P<0.05). Furthermore, the <25μm size of the SiO2-AITC particles prepared by the 35℃vacuum drying demonstrated the best release rate of AITC (89%) when stored at high temperature and high relative humidity (38℃, 98% RH) condition on Day 1. The antimicrobial SiO2-AITC particles have the application as packaging materials used for distribution and storage of food products. The release of AITC can inhibit microbial growth and thus extend the shelf-life of foods.