人類乳突瘤病毒的基礎病毒學

HPV and cervical cancer related articles Part I- HPV basic virology

類乳突瘤病毒（human papilloma virus,HPV）與子宮頸癌關係密切。有足夠證據顯示，HPV就是形成子宮頸癌症最重要原因之一。藉由病毒的研究，對致癌機轉，有了更深一層的了解，同時也將整個婦科癌症的研究範疇，帶入了分子醫學的領域。本系列報導從HPV基礎病毒學開始，首先介紹歷史背景與重要發現，接下來為基本特性、型別區分依據、宿主細胞週期調控、病毒個別基因功能等，一一介紹。

Human papillomavirus (HPV) is strictly related to cervical cancer. There has already been enough evidence that HPV is one of the most important identified causes of cervical cancer. Through comprehensive investigation of HPV, we have a deeper understanding of the carcinogenesis of cervical cancer, and at the same time we advance the research areas of gynecological cancer into the era of modern molecular medicine. This series of reports begin from the HPV basic virology. Firstly, we introduce its historical background and important findings, followed by the basic viral characteristics of the typing, host cell cycle regulation and the respective viral gene function etc.