甲褶鏡應用於全身性硬化症合併雷諾氏現象的診斷價值─初步研究報告

Diagnostic value of nailfold capillaroscopy to systemic sclerosis with Raynaud’s phenomenon: a preliminary study

目的：研究甲褶鏡用於全身性硬化症診斷上的敏感性、特異性、陽性預測值、以及陰性預測值。方法：我們搜尋臺大醫院資料庫中，從西元2007年到2008年中，有雷諾式現象並接受甲褶鏡檢查的病例，分析其在全身性硬化症的診斷經驗。結果：33位病患符合有雷諾式現象並接受甲褶鏡檢查的病例進行分析研究。甲褶鏡用於全身性硬化症診斷上的敏感性為84.62%；特異性為75%；陽性預測值為68.75%；陰性預測值為88.24%。結論：臨床上有雷諾式現象的病例，使用甲褶鏡檢查，其在全身性硬化症上的診斷價值相當高。

Objective: To analyze the sensitivity, specificity, positive predictive value, and negative predictive value of nailfold capillaroscopy to systemic sclerosis with Raynaud’s phenomenon. Methods: The database of the National Taiwan University Hospital was searched for patients with Raynaud’s phenomenon who had been given a nailfold capillaroscopy examination between 2007 and 2008. The medical records were reviewed. Results: The medical records of a total of 33 patients were obtained from the database and the sensitivity and specificity of a scleroderma pattern for systemic sclerosis were 84.62% and 75%, respectively. The positive predictive value and negative predictive value of a scleroderma pattern for systemic sclerosis were 68.75% and 88.24%, respectively. Conclusion: This study is unique in measuring semi-quantitative and qualitative parameters of the nailfold vasculature for systemic sclerosis. The sensitivity, specificity, positive predictive value, and negative predictive value of scleroderma pattern for systemic sclerosis are demonstrated.