停經後婦女骨質疏鬆併發脊椎骨折之臨床表現

Osteoporosis-related Vertebral Fracture in Postmenopausal Women

目的：探討停經後婦女骨質疏鬆併脊椎骨折之臨床表現。方法：自1997至2001年，我們收集了46位停經婦女骨質疏鬆併脊椎骨折之病患。另外我們還取了50位健診的正常停經婦女作為對照組，基本的臨床及生化資料及骨質密度皆有紀錄。結果：患者平均年齡為67歲，最常見的脊椎骨折部位為T12、L1、L2，患者的脊椎及股骨頸部骨質密度皆比正常人為低。最常見的發作年齡為60-75歲。結論：停經後婦女骨質疏鬆併脊椎骨折，最常發生在胸椎和腰椎的交界處，不論脊椎和股骨頸之骨質密度皆比正常人為低。所以早期治療停經後骨質疏鬆的婦女是有必要的。

Objective: To determine the clinical characteristics of osteoporotic – related vertebral fractures in postmenopausal women Methods: Data were collected from patients with osteoporotic-related vertebral fractures from 1997 to 2001. A control group was assembled from those taking health examinations during the same period. Baseline clinical characteristics, biochemical data, and bone mineral density were recorded. Results: Forty-six patients were enrolled. The mean age was 67 years old. The BMI was 25.6 kg/m2. The most common vertebral fractures were at the T12, L1, and L2 levels. The bone mineral density in the group with fractures was lower than that in the normal control group. Conclusions. Vertebral fractures were common at the transition between the thoracic and lumbar spine. The bone mineral density in patients with vertebral fractures was lower than that in the control group, which points to the importance of early treatment in patients with low bone mass.