The current anti-drug strategy in Taiwan, mainly include the establishment of the Central Committee's Drug Prevention Bulletin, Drug Abuse Prevention Center, narcotics hazard prevention act and the use of harm reduction and correction. However, over the years, the issue of drug abuse has not been effectively controlled. In the face of this predicament, the 'new generation anti-drug strategy' is being promoted to create a 'human-centered innovative thinking on drug control.' From drug prevention surveillance, anti-drug prevention, anti-drug traceability, drug rehabilitation strategies, legal amendments and so on. However, the current biggest issue of anti- drug is that the population of new drug users and the original drug user can not be effectively reduced. Nowaday, 'mixed drugs' are rapidly emerging, therefore, the anti-drug strategy should reinforce the primary prevention - happy link to hope and set up an integration of anti-drug specialized agencies, overall decriminalization of drug users is not feasible, and intensified recidivism - from punishment to treatment.