以大黃蟅蟲丸為主方治療骨髓移植後之全身搔癢

Using Rhubarb & Eupolyphaga Formula to Treat Generalized Pruritis after Allogenic Bone Marrow Transplantation

這是一位45歲，因三日發燒不退，於本院診斷為急性骨髓性白血病之中年男性。於2013 年6 月10 日開始五次化學治療，之後於隔年一月進行異體骨髓移植。移植後開始出現全身皮膚搔癢、肌膚甲錯、兩目黯黑、乾枯消瘦、精神困倦、腹滿不能食之狀況，經本院中醫部門診以大黃螫蟲丸為主方治療兩個月後，皮膚搔癢完全消失，肌膚轉為光潤，兩目黯黑情況減輕，體重也增胖八公斤，後續追蹤皮膚搔癢已四個月未曾再發作過。

A 45-year-old male presented to our hospital in June 2013 with 3 days of unremitting fever which was subsequently diagnosed with acute myeloid leukemia. He underwent five courses of chemotherapy and then had allogenic bone marrow transplantation in Jan 2014. As the result, he developed generalized dry skin with pruritis, early satiety and severe weight loss, fatigue, periorbital darkness and abdominal bloating. He was referred to the Chinese medicine department where he was assessed and started on a course of traditional Chinese herbal formula, Rhubarb & Eupolyphaga. At 2 months follow up, he had complete resolution of all symptoms with moist and shinny skin and had regained 8 KGs of body weight. Furthermore, there was no recurrence of skin pruritis at the latest follow up at 4 months.