抗 NMDA 受體腦炎病人的臨床照護經驗

Clinical Experiences of a Female Patient Diagnosed with Anti-NMDA Receptor Autoimmune Encephalitis

The anti-N-methyl D-aspartate receptor (NMDAR) encephalitis showing acute psychosis with catatonic feature and neurological symptoms (including seizure, dyskinesia, speech dysfunction, autonomic instability and breathing dysregulation) has been reported most often in young female adult patients and children with or without ovarian tumor [1, 2]. Autoantibodies target the GluN1 subunit of NMDAR can be detected in the blood and the cerebrospinal fl uid (CSF) in most patients [3]. The longer-term treatment outcome and prognostic factors of anti-NMDAR encephalitis have been of tremendous interest to the neuropsychiatrists.