子宮肌層內之血管收縮素注射引發心搏過慢及心跳停止

Intramyometrial Injection of Vasopressin Causes Bradycardia and Cardiac Arrest-- Report of Two Cases

血管收縮素在婦科手術中已被證實可有效地減少失血量，然而，局部注射血管收縮素卻有可能引發致死性的心肺併發症。我們報告兩例健康女性於接受開腹子宮肌瘤切除術中於局部注射血管收縮素後旋即引發嚴重性的心搏過慢及心跳停止，並在此討論相關的併發症及麻醉的注意事項。

Vasopressin has been documented to effectively reduce blood loss in gynecologic practice. However, local infiltration of vasopressin may cause lethal cardiopulmonary complications in spite of rarity of reported cases. Severe bradycardia and cardiac arrest were encountered after intramyometrial injection of vasopressin in our two healthy patients undergoing open uterine myomectomy. We herewith discuss the associated complications and the anesthetic considerations.