台灣地區市售安比西林(Ampicillin)膠囊製劑力價之調查

AN INVESTIGATION ON THE POTENCY OF AMPICILLIN CAPSULES IN TAIWAN AREA

本局於民國78年度由全省各縣市抽購國產，及進口安比西林（Ampicillin）口服膠囊製劑共50件，其中國產48件，進口2件，依據日本抗生物質醫藥品基準解說（MRAP）上所載之分光光度法及微生物法測定其力價，結果有14件未達合格標準（皆為國產）不合格率為28.0%。

In order to understand the potency of ampicillin capsules, fifty samples (48 domestic, 2 imported) were purchased from different counties and cities in Taiwan during 1989 fiscal year. All of the samples were determined by the cylinder-plate method and optical method as described in the Minimum Requirements for Antibiotic Products of Japan. The results showed that 14 samples (28. 0%) failed to meet the potency requirement of the government regulation (90-120%).