卵巢過度刺激徵候群

Ovarian Hyperstimulation Syndrome

使用人工生犆科技懷孕易產生卵巢過度刺激微候群，對強照追求子賜的婦女而言，是很大的身心壓力。注射人類絨毛膜性腺激素後可能會使得血液中血管上皮因子的濃度上升，此因子會使血管通透性增加，血管內的液體跑至第三腔室，而造救卵巢過度刺激微候群令人不適的徵狀。會產生卵巢過度刺激微候群的危險因子包括：對人類絨毛膜性腺激素故為驅動排卵者、體外受精次數、過敏史。雖然發生卵巢過度刺激微候群並沒有比較好的治療方式，但是依病情程度的不同予以不同的治療，才能對症狀的緩解及減輕不適上有所助益。本文整合相關文獻資料，提供徵候群的概述並介紹治療方式，希望提昇臨席工作人員對此徵候群之了解，以做為日後護理照護之參考。

Assisted conception in patients with ovarian hyperstimulation syndrome is a large stress. Serum vascular endothelial growth factor concentrations rise in HCG administration. Vascular endothelial growth factor is an endothelial cell mitogen with angiogenic properties and is a mediator of ovarian hyperstimulation syndrome. The defect in ovarian hyperstimulation syndrome is altered capillary permeability, which results in increased capillary leakage of fluid into the third space. The risk factors associated with ovarian hyperstimulation syndrome are: a sensitive ovarian response to ovulation induction agents, the age of the patient, the administration of human chorionic gonadotrophin to trigger the ovulatory process, the frequency of assisted conception, patient's allergic history. The treatment is supportive, aiming at limiting and alleviating symptoms.