特殊澱粉製品對於糖尿病患血糖控制之作用

Case Report: Evaluating the Effects of PPBR-203(Special Resistant Starch Product) on the Glycemic Control of a Diabetic Patient by Continuous Glucose Monitoring System

本病例報告的對象為有十年以上病史之糖尿病患者，以PPB-R-203（Slim Keeper）特殊澱粉製品與市售澱粉製品作比較，利用連續血糖監測系統（CGMS），連續監測受試者全天候的血糖值變化。藉此評估此特殊澱粉對於糖尿病患血糖控制的影響。PPB-R-203（Slim Keeper）是以多種穀類磨成粉後，經多次加溫加壓的特殊製程而提高穀粉中難消化性澱粉（如：抗性澱粉及直鏈澱粉）的含量，再製成多穀麵、多穀米及多穀餅乾等特殊澱粉製品。另外，連續血糖監測系統（CGMS）是目前已被美國食品藥物檢驗局（FDA）核准的血糖偵測工具；藉由此種新裝置可以得到連續不間斷的血糖值，幫助糖尿病患能及時掌握血糖的變化，達到更容易控制血糖的目的。本病例報告顯示特殊澱粉製品，如PPB-R-203（Slim Keeper），能幫助長期血糖控制不良的糖尿病患，血糖值相對維持穩定，具有消峰去谷之效果；藉由降低餐後高血糖以及低血糖（尤其是半夜低血糖）的情況，PPB-R-203（Slim Keeper）一類的特殊澱粉製品的確對於幫助維持糖尿病患血糖的穩定具有正面的效果。除了運動及藥物控制外，在糖尿病患飲食中補充此類難消化性特殊澱粉及膳食纖維相信可以為糖尿病患提供更容易控制血糖的途徑。

By continuous glucose monitoring system(CGMS), the effects of PPB-R-203(special resistant starch product) on the glycemic control of a diabetic patient will be discussed in this case report. Our subject is a 42-year-old male with the history of diabetes and hypertension. At present, this patient receives insulin injection for adjusting his blood glucose level. In this case, the patient took either PPB-R-203 or commercial starch product as meals and the glycemic variability of both conditions would be monitored by CGMS. By means of CGMS, the blood glucose level of the subject was monitored all day long. In this way, we were able to detect the blood glucose level consecutively and compare the effects between PPB-R-203 and commercial starch product. PPB-R-203 was made up of barley, wheat germ, oats, buckwheat, maize and unpolished rice. After grinding all these component to powder, the content of resistant starch was elevated through seven stages of heating and pressing processes. In the end, the processed powder was used to produce rice, noodles and crackers. This case report indicated that intake of PPB-R-203 could decrease the elevation of blood glucose level after meals. On the other hand, PPB-R-203 intake could also improve the hypoglycemia caused by insulin treatment. That is, PPB-R-203 could stabilize the level of blood glucose in the diabetic patient receiving insulin injection. In conclusion, the resistant starch products, such as PPB-R-203, could be added to the meals of diabetic patients for a better glycemic control.