嚴重精神病病人短期運動介入對代謝指標及骨質密度的影響

Effects of Short-term Exercise Intervention on Metabolic Features and Bone Mineral Density in Patients with Serious Mental Illnesses

目的：統計顯示代謝症候群和骨質疏鬆症在嚴重精神病病人的高盛行率。此前瞻性研究 探討運動對台灣某社區型醫院嚴重精神病患者上述疾患之可能療效。方法：檢視 12 週有氧 運動對嚴重精神病病人之代謝指標及骨密度之影響。結果：20 名患者於運動介入前代謝症 候群，骨質疏鬆及骨質缺乏之盛行率分別為 40%，15.8% 和 42.1%。14 名病人完成此試驗。 介入前後，個別代謝指標和區域骨密度的變化沒有顯著差異，代謝指標和腰椎骨密度並無顯 著相關。結論：結果支持代謝症候群和骨質疏鬆症在嚴重精神病患者的高盛行率及監測和介 入之必要性。運動介入之療效需要進一步評估。

Objectives: Epidemiologic evidence suggests that patients with serious men- tal illnesses are at higher risk for metabolic syndrome (MS) and osteoporosis. In this prospective study, we intended to examine the effectiveness of short-term ex- ercise intervention program for patient with those disturbances. Methods: We ex- amined the effects of a supervised 12-week aerobic exercise program on metabolic indices and bone mineral density in patients with serious mental illnesses. Results: Among 20 patients recruited, we found that the prevalences of MS, osteoporosis and osteopenia were 40%, 15.8%, and 42.1%, respectively, at baseline. Fourteen participants completed the program. There was no significant change in metabolic indices and bone mineral density after a short-term exercise intervention. Besides, the correlation between individual metabolic index and bone mineral density was not significant. Conclusion: The study results supported the necessity for close monitoring MS and osteoporosis as well as giving intervention in patients with serious mental illnesses. The effectiveness of exercise intervention warrants fur- ther evaluation.