This article recounts our nursing experience with a 80 year old male patient suffering from lung cancer with pleural effusion and negative feeling caused by the unpredictability of the disease progression and the insertion of a long term drain. During the nursing period (Jan. 2nd to Jan. 18th 2012), we interviewed and carefully observed the patient and evaluated his physical condition based on “Gordon’s 11 Functional Health Patterns”. The pleural effusion caused shortness of breath, and the patient was anxious about the uncertainty of his disease progression. He needed to have a long term drain and was embarrassed about the smell from it and felt ashamed. The patient lived with his wife who was his only caregiver; they depended on each other and no one shared the care work. His wife was afraid that she could not offer him proper care and was exhausted. We not only took care of the patient with terminal cancer but were actively concerned about his caregiver. First, we made the patient feel comfortable during the nursing process and then relieved his shortness of breath and addressed his anxiety. We taught the patient and his caregiver how to care for the drain and reduce the odor of the wounds. Then, we helped the patient accept the changes in his appearance cause by placement of the drain. We believe that his wife had less stress as long as she knew how to properly care for the patient. We suggest that clinical care of a terminal cancer patient should focus not only on the patient but also include concern for the primarily caregiver in order to achieve a better quality of care.