Kikuchi's disease is a rare, benign condition of unknown etiology and is usually characterized by fever and cervical lymphadenopathy. A 31 year-old female had intermittent fever and a left cervical mass. These symptoms persisted for 2 months in spite of management with supportive treatment in a local medical clinic. When a tender, right post-auricular mass lesion was noted, she presented at our hospital. Neck CT showed multiple lymphadenopathy in bilateral post-cervical areas. The largest lymph node measured 2.2 × 1.2 cm. Fine needle aspiration cytology showed many inflammatory cells but no malignant cells. In order to exclude malignancy such as lymphoma, excisional biopsy of a left neck lymph node was done and pathology showed necrotizing lymphadenitis (Kikuchi's disease). After treatment with a low-dose steroid, NSAID and acetaminophen for 2 weeks, her fever and neck mass gradually subsided and no recurrence was found at 1-year follow-up. Because patients with Kikuchi's disease may develop systemic lupus erythematosis (SLE) or recurrences of Kikuchi's disease, they should be followed up for several years.