空氣中五種除蟲菊類及魚藤精農藥同時分析方法之研究

A Study on Simultaneous Analysis for Pyrethrins and Rotenone Pesticides in Air Sample

本研究的目的在於建立五種除蟲菊類農藥，賽洛寧（Cyhalothrin）、賽滅寧（Cypermethrin）、第滅寧（Deltamethrin）、百滅寧（Permethrin） 、除蟲菊精（Pyrethrum）及魚籐精（Rotenone）等藥劑分別以 OVS-2（OSHA versatile sampler-2）吸附管及PTFE（polytetrafluoroethylene）濾紙為採樣介質，以乙腈為萃取溶劑，超音波振盪過濾後並以高效液相層析儀附紫外光檢測器（HPLC-UV）及氣相層析儀附質譜儀檢測器（GC-MSD）之測定方法，俾應用於農藥工廠作業環境測定。五種除蟲菊類農藥及一種魚籐精添加於 OVS-2 吸附管上連續抽氣 2 小時，回收率皆大於 73.51%，其變異係數亦小於 7.39%。將農藥添加於 OVS-2 吸附管上進行貯存試驗及冷藏貯存試驗時，所有藥劑貯存穩定度皆達二十八天。添加於 PTFE 濾紙上連續抽氣 2 小時，結果之回收率皆大於 74.73%，其變異係數亦小於 18.7%。將農藥添加於 PTFE 濾紙上進行 28 天貯存試驗及冷藏貯存試驗時，所有藥劑貯存穩定度亦均達二十八天以上。測定空氣中多種農藥含量其偵測極限低於 1/375~1/30 倍之公告容許濃度標準（PEL） 。兩種採樣分析新技術可適用於五種除蟲菊類及一種魚籐精農藥作為實際農藥工廠作業環境測定應用。

An air sampling and analytical method was developed for Cyhalothrin, Cypermethrin, Deltamethrin, Permethrin, Pyrethrins and Rotenone pesticides using a combined quatze filter and XAD-2 sorbent (OVS- 2), and PTFE filter, with acetonitrile as the extraction solvent and High Performance Liquid Chromatography-Ultraviolet detection. The method was evaluated for 5 pyrethroids pesticides and a rotenone pesticide for risk assessment of workers at pesticide manufacturing factories. The recovery rates of acetronitrile extraction of 5 pyrethroids pesticides and a rotenone pesticide from OVS-2 and PTFE samples are greater than 73.51% and 74.73% respectively and coefficient of variation is less than 7.39% and 18.73%, respectively. Additional experiments addressed long-term sample stability (28-day storage), limits of detection, and concentration levels down to 1/375~1/30 times of permissible exposure limits (PEL) value. Based on these results, all 6 compounds studied can be successfully determined simultaneously using either method.