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篇名
針刺臨床試驗治療失眠症的經驗分享
並列篇名
Clinical Acupuncture Trial on Insomnia Patients--A Taiwan Experience
作者 江裕陽許恆壹謝瓊慧林在裕蔡盧浚陳珮青
中文摘要
目的:1.針刺療法與西藥Stilnox(俗名-Zolpidem)治療失眠症的療效比較。2. 針刺療法與西藥Stilnox合併使用治療失眠症是否更具療效。方法:自2007年8月至2008年5月,以隨機對照試驗 (Randomized Controlled Trial, RCT)方式收案,在臺北市立聯合醫院中興院區進行臨床試驗。參加者被隨機分為A組 (每天睡前服用5毫克Stilnox)、B組 (每天睡前服用5毫克Stilnox,並每週接受針刺治療3次) 及C組 (未服藥,僅每週接受針刺治療3次) 三組。治療期間為4週,並於治療後4週,接受隨訪(follow up)。受試者治療前及每週治療後均接受匹茲堡睡眠品質量表(PSQI)的療效評估。結果:總共有48位參加臨床試驗,其中未完成療程即退出者有28人,完成療程及追訪之受試者共20人,包括A組2人,B組10人,C組8人。治療結果顯示,B組或C組受試者在接受針刺治療三週及四週後的PSQI分數,與治療前的PQSI分數作比較,在統計學上均具有顯著的差異存在(P<0.05),且在治療後四週追訪時,其療效然存在。而B組與C組兩組間,則無統計上顯著差異(P=0.73)。結論:本研究受限於樣本數太小及高退出率,單獨採用針刺療法或合併使用Stilnox治療失眠症的療效仍不確定,但初步資料顯示,利用針刺治療失眠症,可能有其潛在的效益存在。Objective: The aims of this study were to examine whether acupuncture is better than/same as Stilnox (Generic name-Zolpidem) and whether combination of acupuncture with Stilnox is better than/same as acupuncture alone or Stinox alone. Methods: A randomized controlled trial was conducted from August 2007 to May 2008 in Zhong-Xing Branch , Taipei City Hospital, Taiwan. The participants were randomly assigned into one of the three groups for a 4-week intervention and a 4-week follow-up after treatments. Treatment of the participants was given on a weekly basis. Group A took Stilnox 5mg/day at bedtime. Group B took Stilnox 5mg/day at bedtime and received acupuncture 3 times a week. Group C took no medication but received acupuncture 3 times a week. The effectiveness of treatments of the three groups was all evaluated weekly by the Pittsburgh sleep quality index (PSQI). Results: A total of 48 participants were initially enrolled. Among them, 28 withdrew during the study. The remaining 20 participants, including 2 of Group A, 10 of Group B and 8 of Group C, completed the entire treatment course and were evaluated. The result showed that the PSQI value decreased significantly (p < 0.05) compared with baseline after 3-week intervention and 4-week intervention in both Group B (n=10) and Group C (n=8). The effects of treatments were still maintained at the 4-week follow-up after treatments. There was no significant difference(p = 0.73) in terms of effectiveness of treatment between Group B and Group C. Conclusions: The effectiveness of acupuncture alone or in combination with Stilnox remains uncertain, because of the small sample size and high drop-out rate, especially in the medication-only group. The initial data may reveal potential beneficial effects of acupuncture in treating insomnia.
起訖頁 35-45
關鍵詞 菊科藥用植物植物化學成分研究臺灣1996年-2005年AsteraceaeMedicinal plantsPhytochemical studyTaiwan1996-2005
刊名 中醫藥雜誌  
期數 200907 (20:1-2期)
出版單位 衛生福利部國家中醫藥研究所(原:國立中國醫藥研究所)
該期刊-上一篇 中醫門診肝病患者中藥製劑用藥頻率與形態分析
該期刊-下一篇 傷寒論之欲解時析辨
 

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