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篇名
懷牛膝成分研究
並列篇名
Studies on the Chemical Constituents of Achyranthes Bidentata B(subscript LUME)
作者 張永勳陳啟源何禮剛
中文摘要
懷牛膝(Achyranthes bidentata BLUME)為莧科植物牛膝之乾燥根,具有鎮痛抗發炎、利尿、抗菌及抗痙攣之作用,並對於腰膝酸痛、強筋骨、補肝腎方面有很好的效果。懷牛膝(Achyranthes bidentata BLUME)的甲醇抽出物,經分離及結構分析,鑑定得到14個化合物,分別是stigmasterol和β-sitosterol的混合物 paeonol、palmitic acid、physcion、chrysophanol、stigmasterol-3-O-b-D-glucoside和β-sitosterol-3-O-β-D-glucoside之混合物、oleanolic acid、5-(hydroxymethyl)-furfural、1-palmityl glycerol、N-trans-feruloyl 3-methyldopamine、oleanolic acid 3-O-β-D-glucuronopyranoside 6' methyl ester、ecdysterone;其中paeonol、chrysophanol、5-(hydroxymethyl)-furfural、1-palmityl glycerol、N-trans-feruloyl-3-methyldopamine五個化合物為Achyranthes屬植物中首次分離到。
英文摘要
Achyranthes bidentata B is one of the plant of Amaranthaceae family and possesses analgesic, anti-inflammatory, diuretic, anti-bacterical and anti- convulsive activities. It was used to cure knee pain and strengthen sinews and bones and also as tonic supplements for liver and kidney. The methanolic extract of this herb was partitioned and separated by chromatographic methods. Fourteen components were obtained. By analyzing their physical, chemical and spectral data, these components were identified as a mixture of stigmasterol and β-sitosterol, paeonol, palmitic acid, physcion, chrysophanol, another mixture of stigmasterol-3-O-β-D-glucoside and β-sitosterol-3-O-β-D- glucoside, oleanolic acid, 5-(hydroxymethyl)-furfural, 1-palmityl glycerol, N- trans-feruloyl 3-methyldopamine, oleanolic acid-3-O-β-D-glucuronopyranoside 6'- methyl ester as well as ecdysterone. Among these compounds, paeonol, chrysophanol, 5-(hydroxymethyl)-furfural, 1-palmityl glycerol, N-trans-feruloyl-3- methyldopamine were isolated from Achyranthes genus for the first time.
起訖頁 177-187
關鍵詞 懷牛膝paeonolchrysophanol5-hydroxymethyl-furfural1-palmityl glycerolN-trans-feruloyl-3-methyldopamineAchyranthes bidentataPaeonolChrysophanol5-Hydroxymethyl-furfural1-Palmitylgl glycerolN-trans-Feruloyl-3-methyldopamine
刊名 中醫藥雜誌  
期數 199709 (8:3期)
出版單位 衛生福利部國家中醫藥研究所(原:國立中國醫藥研究所)
該期刊-上一篇 臺灣市售牛膝類藥材之藥理學研究
 

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