This study used ”ryodoraku” to detect the ”source point” of the twelve meridians and compared the change of ryodoraku value according to related factors. The stroke patient is said to have ryodoraku value lower than normal, so we tried to evaluate the change of values according to the sex, age and case of the stroke patient. We recorded the ryodoraku values of the twelve meridians, according to the sex, age and case of the stroke each meridian for all patients, and compared the readings by the statistical method of multiple lin-ear regression. The results show that: (1) The ryodoraku value is significantly lower in females than in males in both the experimental and control group (p＜0.001). (2) The ryodoraku value of spleen or bladder meridian in the control group varies in inverse proportion with age (p＜0.01). The same inverse proportion relationship is found between the age and the ryodoraku value of eight meridians included lung, small intestine, spleen, stomach, liver, gallbladder, kidney and bladder in experimental group. (3) Although there are no significant differences between thrombotic and hemorrhagic type in experimental group, their value was lower than those in control group (p＜0.05). (4) The change of value in twelve meridians is significantly inverse proportion with age, thrombotic or hemorrhagic type in experimental group (p＜0.01). The results of this study shows that age and cause of stroke patient can lower their ryodoraku value. Sex is not the main factor. This result provides some reference for evaluation of stroke patients using ”ryodoraku”.