肺癌病患在化學治療期間疲憊程度及其相關因素

Fatigue Levels and Related Factors in Lung Cancer Patients During Chemotherapy

本研究針對肺癌病患接受化學治療期間疲憊程度及其相關因素作探討，採橫斷式相關設計，以東部、北部及西部各一所準教學以上之醫院的肺癌病患為研究對象，共收得75份有效之問卷。研究結果發現肺癌病患接受化學治療期間，承受中等程度之疲憊，疲憊發生率僅次於咳嗽，但卻最嚴重困擾病患。同時，病患有輕度的憂鬱，症狀困擾亦屬輕度。病患之化學治療療程、化學治療後的天數與疲憊程度達顯著性差異，血色素數值則與疲憊程度呈負相關。症狀困擾及憂鬱程度皆與疲憊程度之間呈顯著的正相關，且可做為疲憊感的重要預測因子，可解釋47.8%的變異量。本研究結果將有助於臨床醫護人員瞭解病患症狀困擾及憂鬱感是疲憊照護的重點之一，藉此以達病患生活品質之改善。

The purpose of this research is to study fatigue level and its related factors of lung cancer patients during chemotherapy. A cross-sectional correlation design and purposive sampling were used. The patients were recruited from three teaching hospitals, located in the East, the North and the West of Taiwan respectively. A total of 75 valid questionnaires were completed. The result indicated that subjects suffered from a middle level of fatigue during the chemotherapy, and although fatigue was the second major side effect, it is the most bothering factor on the patients. Subjects also hade mild depression and syndrome distress. There are significant differences among the fatigue level, the number of times of chemotherapy and the days after latest chemotherapy. There is a negative correlation between the hemoglobin levels and the fatigue levels. There is a significant positive correlation between the syndrome distress, depression and fatigue. Moreover, syndrome distress and depression are significant predictors of fatigue, accounting for 47.8% of variance. In conclusion, the study demonstrated that fatigue levels were significantly associated with syndrome distress and depression, and the result can offer healthcare provider a guide to improve patient’s quality of life during chemotherapy.