南部某醫學中心健康檢查民眾高尿酸血症之分析

Analysis of Hyperuricemia among Residents Attending a Physical Check-up Program in a Medical Center in Southern Taiwan

本研究目的主要探討健康檢查民眾血中尿酸檢查結果與身體質量指數、血壓、肝功能、腎功能、血中總膽固醇、血中三酸甘油脂、血糖之關係。本研究採橫斷式研究，以2002年1月至2002年6月，參加南部某醫學中心健康檢查的民眾為對象，總計樣本數為2345名，其中男性1345人(57.4％)、女性1000人(42.6％)，平均年齡為49歲。資料收集後進行統計分析，研究結果顯示男性尿酸異常為35.6％較女性尿酸異常25.7％的比例為高。卡方檢定(Chi-square test)顯示尿酸檢查結果與性別、年齡、血壓、身體質量指數、肝功能、腎功能、血中總膽固醇、血中三酸甘油脂、飯前血糖有關，與飯後血糖無關。經邏輯式複迴歸分析發現性別、肥胖、肝功能異常、腎功能異常與血中三酸甘油脂異常與尿酸異常有獨立的正相關。本研究建議醫護人員能加強民眾對健康檢查的重視，有高尿酸血症之民眾應遵循健康生活型態，並且控制體重、血壓，以預防慢性病之發生及提昇生活品質。

In this cross-sectional study, we examined the association between hyperuricemia and body mass index (BMI), blood pressure, blood sugar, total cholesterol, triglyceride, liver and kidney functions. Subjects were residents attending a physical check-up program in a medical center in southern Taiwan from January to June in 2002. A total of 2345 subjects, including 1345 (57.4%) male and 1000 (42.6%) female, with an average age of 49, were included in the analysis. The results showed that the prevalence of hyperuricemia among men was 35.6%, significantly higher than that of the women (25.7%). The results of chi-square analysis showed that hyperuricemia was associated with gender, age, blood pressure, BMI, liver function, kidney function, total cholesterol, triglyceride, and blood sugar before meal. The results of multiple logistic regression revealed that hyperuricemia was independently associated with sex, obesity, kidney and liver functions, and triglyceride level. We suggest healthcare providers emphasizing the importance of regular physical check-up to the public. For those with hyperuricemia, dietary modification and proper control of weight and blood pressure are advised to prevent the occurrence of chronic diseases.