闌尾杯狀細胞類癌瘤合併急性闌尾炎：病例報告及文獻分析

Goblet Cell Carcinoid of Appendix with Acute Appendicitis: Case Report and Review of Literature

杯狀細胞類癌瘤又稱為腺類癌瘤是非常罕見的闌尾惡性腫瘤，本文報告一位51歲男性患者因腹痛疑似急性盲腸（闌尾）炎，接受緊急闌尾切除。切除的闌尾巨觀下與一般急性化膿性闌尾炎無異，但是病理檢查發現杯狀細胞類癌瘤已侵犯闌尾全層，並擴散至漿膜下層。病人也在病理確診後進一步接受右側結腸切除治療。因此詳細的病理檢查，正確診斷杯狀細胞類癌瘤，區分其與尋常類癌瘤的差異，使病人接受後續的癌症治療與追蹤是非常重要。

Goblet cell carcinoid (GCC), also named adenocarcinoid tumor, is a rare and aggressive malignant tumor of the appendix. We reported a case of a 51 year-old man presenting with acute appendicitis, but pathologically diagnosed as goblet cell carcinoid. Grossly, the outer aspect of resected appendix was involved by acute inflammation, with thick purulent coating and marked hyperemia serosa. Microscopic examination showed not only acute suppurative appendicits, but also an infiltrating tumor diffusely invading the appendiceal wall and extending into the mesoappendix. The patient received further right hemicolectomy due to diagnosis of appendiceal goblet cell carcinoid, with invasion into the mesoappendix. Careful pathological examination is warranted as further surgery and follow up are necessary for this aggressive tumor.