異位性皮膚炎患者使用中醫藥型態分析研究

A Study on the Characteristics of Traditional Chinese Medicine Use for Patients with Atopic Eczema

目的：異位性皮膚炎是一個慢性反覆發作的過敏性疾病，病患經常使用中醫藥治療，然而臨床上卻缺乏充足的實證與治療共識，此研究目的為分析探討異位性皮膚炎患者就診中醫的特色與用藥型態。方法：我們回溯收集2003 年至2011 年期間長庚紀念醫院異位性皮膚炎病患病歷。統計分析異位性皮膚炎患者的基本資料、治療期間、治療頻率、血清總免疫球蛋白E 濃度及中藥處方。結果：我們發現於2003 年至2011 年，有3848 位患者（占所有異位性皮膚炎患者之8.92%）曾經求診中醫，其中2599 位（67.54%）選擇接受單一中醫治療。最常見的合併疾病為過敏性鼻炎（46.60%）與氣喘（21.32%）。而在81443 次的中藥方劑裡，消風散（16.66%）是最常被使用的方劑。單味藥物則以白蘚皮（12.86％）為最多。結論：本研究探討異位性皮膚炎病患於醫學中心就診中醫門診特色，並分析中醫師選用中藥治療異位性皮膚炎之經驗，可作為未來中醫藥臨床研究療效及安全性之參考。

Background: Atopic eczema is a chronic, pruritic and relapsing skin disease. Traditional Chinese medicine use for atopic eczema is not uncommon. However, large-scale studies and general agreement on treating atopic eczema by Chinese medicine are lacking.
Objective: The aim of this study is to investigate the characteristics and utilization of traditional Chinese medicine in patients with atopic eczema in a medical center.
Methods: We retrospectively collected medical records of patients with atopic eczema at the Chang Gung Memorial Hospital in Taiwan between 2003 and 2011. Data including demographic data, treatment duration, serum total immunoglobulin Elevels, and prescription were examined.
Results: Overall, 3,848 patients (8.92% of all patients with atopic eczema) received traditional Chinese medicine between 2003 and 2011. Among these patients, 2,599 (67.54%) only used TCM therapy and 1,249 (32.46%) chose to combine TCM and WM therapies. The most frequent comorbidities are allergic rhinitis (46.60%) and asthma (21.32%). There were totally 81,443 prescriptions and the most common herbal formula and single herb were Xiao-Feng-San (16.66%) and Bai-Xian-Pi (Cortex Dictamni) (12.86%), respectively.
Conclusion: This single medical center-based study investigated the prescription patterns of traditional Chinese medicine in atopic eczema patients. The information could be used as references for basic and clinical studies in the future.