The purpose of this quantitative study is to explore the relationship between perceived pressure and social support in parents of children with epilepsy. Researchers recruited parents of children with epilepsy at the pediatric neurology clinic of Changhua Christian Hospital. Several scales including the demographic data of children and their parents, the Perceived Stress Scale, and social support scale were used to collect data. All data were encoded into computer, and analyzed with the SPSS 15.0 packaged software. This study recruited fifty-six mothers and nineteen fathers. The results revealed that parents' perceived stress was not high, but parents were short of social supports, especially informational support about child development and how to nurture sick children. Major sources of social support came from family, friends, and professionals. Instrumental and emotional support mostly came from the family, whereas informational support came from professionals. Our findings suggested that health care workers should actively explore the needs of parents of child with epilepsy and give appropriate information in nursing care. Future study should develop intervention methods to improve the ability for seeking social support in parents of children with epilepsy.